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Incorporating Functional Genomic Information in Genetic Association Studies Using an Empirical Bayes Approach

There is a large amount of functional genetic data available, which can be used to inform fine‐mapping association studies (in diseases with well‐characterised disease pathways). Single nucleotide polymorphism (SNP) prioritization via Bayes factors is attractive because prior information can inform...

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Detalles Bibliográficos
Autores principales:	Spencer, Amy V., Cox, Angela, Lin, Wei‐Yu, Easton, Douglas F., Michailidou, Kyriaki, Walters, Kevin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832271/ https://www.ncbi.nlm.nih.gov/pubmed/26833494 http://dx.doi.org/10.1002/gepi.21956

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