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Rational Design of Antirheumatic Prodrugs Specific for Sites of Inflammation
OBJECTIVE: Biologic drugs, such as the anti–tumor necrosis factor (anti‐TNF) antibody adalimumab, have represented a breakthrough in the treatment of rheumatoid arthritis. Yet, concerns remain over their lack of efficacy in a sizable proportion of patients and their potential for systemic side effec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832285/ https://www.ncbi.nlm.nih.gov/pubmed/26097196 http://dx.doi.org/10.1002/art.39232 |