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Distinct expression patterns for type II topoisomerases IIA and IIB in the early foetal human telencephalon
TOP2A and TOP2B are type II topoisomerase enzymes that have important but distinct roles in DNA replication and RNA transcription. Recently, TOP2B has been implicated in the transcription of long genes in particular that play crucial roles in neural development and are susceptible to mutations contr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832326/ https://www.ncbi.nlm.nih.gov/pubmed/26612825 http://dx.doi.org/10.1111/joa.12416 |