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A benzamide‐dependent fts Z mutant reveals residues crucial for Z‐ring assembly

In almost all bacteria, cell division is co‐ordinated by the essential tubulin homologue FtsZ and represents an attractive but as yet unexploited target for new antibiotics. The benzamides, e.g. PC190723, are potent FtsZ inhibitors that have the potential to yield an important new class of antibioti...

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Detalles Bibliográficos
Autores principales: Adams, David William, Wu, Ling Juan, Errington, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832351/
https://www.ncbi.nlm.nih.gov/pubmed/26601800
http://dx.doi.org/10.1111/mmi.13286