CHD1L Regulated PARP1‐Driven Pluripotency and Chromatin Remodeling During the Early‐Stage Cell Reprogramming

PARP1 and poly(ADP‐ribosyl)ation (PARylation) have been shown to be essential for the initial steps of cellular reprogramming. However, the mechanism underlying PARP1/PARylation‐regulated activation of pluripotency loci remains undetermined. Here, we demonstrate that CHD1L, a DNA helicase, possesses...

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Detalles Bibliográficos
Autores principales: Jiang, Bo‐Hua, Chen, Wei‐Yi, Li, Hsin‐Yang, Chien, Yueh, Chang, Wei‐Chao, Hsieh, Pei‐Chen, Wu, Ping, Chen, Chieh‐Yu, Song, Hui‐Yung, Chien, Chian‐Shiu, Sung, Yen‐Jen, Chiou, Shih‐Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832376/
https://www.ncbi.nlm.nih.gov/pubmed/26201266
http://dx.doi.org/10.1002/stem.2116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832376/
https://www.ncbi.nlm.nih.gov/pubmed/26201266
http://dx.doi.org/10.1002/stem.2116

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