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CHD1L Regulated PARP1‐Driven Pluripotency and Chromatin Remodeling During the Early‐Stage Cell Reprogramming
PARP1 and poly(ADP‐ribosyl)ation (PARylation) have been shown to be essential for the initial steps of cellular reprogramming. However, the mechanism underlying PARP1/PARylation‐regulated activation of pluripotency loci remains undetermined. Here, we demonstrate that CHD1L, a DNA helicase, possesses...
Autores principales: | Jiang, Bo‐Hua, Chen, Wei‐Yi, Li, Hsin‐Yang, Chien, Yueh, Chang, Wei‐Chao, Hsieh, Pei‐Chen, Wu, Ping, Chen, Chieh‐Yu, Song, Hui‐Yung, Chien, Chian‐Shiu, Sung, Yen‐Jen, Chiou, Shih‐Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832376/ https://www.ncbi.nlm.nih.gov/pubmed/26201266 http://dx.doi.org/10.1002/stem.2116 |
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