Cargando…

Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis

Cathepsin B is a cysteine proteinase that primarily functions as an endopeptidase within endolysosomal compartments in normal cells. However, during tumoral expansion, the regulation of cathepsin B can be altered at multiple levels, thereby resulting in its overexpression and export outside of the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Bian, Benjamin, Mongrain, Sébastien, Cagnol, Sébastien, Langlois, Marie‐Josée, Boulanger, Jim, Bernatchez, Gérald, Carrier, Julie C., Boudreau, François, Rivard, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832390/
https://www.ncbi.nlm.nih.gov/pubmed/25808857
http://dx.doi.org/10.1002/mc.22312