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Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis
Cathepsin B is a cysteine proteinase that primarily functions as an endopeptidase within endolysosomal compartments in normal cells. However, during tumoral expansion, the regulation of cathepsin B can be altered at multiple levels, thereby resulting in its overexpression and export outside of the c...
Autores principales: | Bian, Benjamin, Mongrain, Sébastien, Cagnol, Sébastien, Langlois, Marie‐Josée, Boulanger, Jim, Bernatchez, Gérald, Carrier, Julie C., Boudreau, François, Rivard, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832390/ https://www.ncbi.nlm.nih.gov/pubmed/25808857 http://dx.doi.org/10.1002/mc.22312 |
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