Recessive mutations in the cancer gene Ataxia Telangiectasia Mutated (ATM), at a locus previously associated with metformin response, cause dysglycaemia and insulin resistance

AIM: To investigate glucose and insulin metabolism in participants with ataxia telangiectasia in the absence of a diagnosis of diabetes. METHODS: A standard oral glucose tolerance test was performed in participants with ataxia telangiectasia (n = 10) and in a control cohort (n = 10). Serial glucose...

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Detalles Bibliográficos
Autores principales: Connelly, P. J., Smith, N., Chadwick, R., Exley, A. R., Shneerson, J. M., Pearson, E. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832393/
https://www.ncbi.nlm.nih.gov/pubmed/26606753
http://dx.doi.org/10.1111/dme.13037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832393/
https://www.ncbi.nlm.nih.gov/pubmed/26606753
http://dx.doi.org/10.1111/dme.13037

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