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The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing
BACKGROUND: The cohesin complex consists of multiple core subunits that play critical roles in mitosis and transcriptional regulation. The cohesin-associated protein Wapal plays a central role in off-loading cohesin to facilitate sister chromatid separation, but its role in regulating mammalian gene...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832553/ https://www.ncbi.nlm.nih.gov/pubmed/27087855 http://dx.doi.org/10.1186/s13072-016-0063-7 |