Beyond comparisons of means: understanding changes in gene expression at the single-cell level

Traditional differential expression tools are limited to detecting changes in overall expression, and fail to uncover the rich information provided by single-cell level data sets. We present a Bayesian hierarchical model that builds upon BASiCS to study changes that lie beyond comparisons of means,...

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Detalles Bibliográficos
Autores principales: Vallejos, Catalina A., Richardson, Sylvia, Marioni, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832562/
https://www.ncbi.nlm.nih.gov/pubmed/27083558
http://dx.doi.org/10.1186/s13059-016-0930-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832562/
https://www.ncbi.nlm.nih.gov/pubmed/27083558
http://dx.doi.org/10.1186/s13059-016-0930-3

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