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Beyond comparisons of means: understanding changes in gene expression at the single-cell level
Traditional differential expression tools are limited to detecting changes in overall expression, and fail to uncover the rich information provided by single-cell level data sets. We present a Bayesian hierarchical model that builds upon BASiCS to study changes that lie beyond comparisons of means,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832562/ https://www.ncbi.nlm.nih.gov/pubmed/27083558 http://dx.doi.org/10.1186/s13059-016-0930-3 |