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Investigating the Influence of (Deoxy)fluorination on the Lipophilicity of Non‐UV‐Active Fluorinated Alkanols and Carbohydrates by a New log P Determination Method

Property tuning by fluorination is very effective for a number of purposes, and currently increasingly investigated for aliphatic compounds. An important application is lipophilicity (log P) modulation. However, the determination of log P is cumbersome for non‐UV‐active compounds. A new variation of...

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Detalles Bibliográficos
Autores principales: Linclau, Bruno, Wang, Zhong, Compain, Guillaume, Paumelle, Vincent, Fontenelle, Clement Q., Wells, Neil, Weymouth‐Wilson, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832822/
https://www.ncbi.nlm.nih.gov/pubmed/26592706
http://dx.doi.org/10.1002/anie.201509460