Exome‐wide single‐base substitutions in tissues and derived cell lines of the constitutive Fhit knockout mouse

Loss of expression of Fhit, a tumor suppressor and genome caretaker, occurs in preneoplastic lesions during development of many human cancers. Furthermore, Fhit‐deficient mouse models are exquisitely susceptible to carcinogen induction of cancers of the lung and forestomach. Due to absence of Fhit g...

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Detalles Bibliográficos
Autores principales: Paisie, Carolyn A., Schrock, Morgan S., Karras, Jenna R., Zhang, Jie, Miuma, Satoshi, Ouda, Iman M., Waters, Catherine E., Saldivar, Joshua C., Druck, Teresa, Huebner, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832848/
https://www.ncbi.nlm.nih.gov/pubmed/26782170
http://dx.doi.org/10.1111/cas.12887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832848/
https://www.ncbi.nlm.nih.gov/pubmed/26782170
http://dx.doi.org/10.1111/cas.12887

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