Cetuximab delivery and antitumor effects are enhanced by mild hyperthermia in a xenograft mouse model of pancreatic cancer

Even with current promising antitumor antibodies, their antitumor effects on stroma‐rich solid cancers have been insufficient. We used mild hyperthermia with the intent of improving drug delivery by breaking the stromal barrier. Here, we provide preclinical evidence of cetuximab + mild hyperthermia...

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Detalles Bibliográficos
Autores principales: Miyamoto, Ryoichi, Oda, Tatsuya, Hashimoto, Shinji, Kurokawa, Tomohiro, Inagaki, Yuki, Shimomura, Osamu, Ohara, Yusuke, Yamada, Keiichi, Akashi, Yoshimasa, Enomoto, Tsuyoshi, Kishimoto, Mikio, Yanagihara, Hideto, Kita, Eiji, Ohkohchi, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832851/
https://www.ncbi.nlm.nih.gov/pubmed/26782353
http://dx.doi.org/10.1111/cas.12888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832851/
https://www.ncbi.nlm.nih.gov/pubmed/26782353
http://dx.doi.org/10.1111/cas.12888

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