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Combined adjuvants of poly(I:C) plus LAG‐3‐Ig improve antitumor effects of tumor‐specific T cells, preventing their exhaustion

Therapeutic cancer vaccines are designed to treat cancer by boosting the endogenous immune system to fight against the cancer. In the development of clinically effective cancer vaccines, one of the most practical objectives is to identify adjuvants that are capable of optimizing the vaccine effects....

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Detalles Bibliográficos
Autores principales: Kano, Yosuke, Iguchi, Takahiro, Matsui, Hiroto, Adachi, Keishi, Sakoda, Yukimi, Miyakawa, Tomoya, Doi, Shun, Hazama, Shoichi, Nagano, Hiroaki, Ueyama, Yoshiya, Tamada, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832865/
https://www.ncbi.nlm.nih.gov/pubmed/27079438
http://dx.doi.org/10.1111/cas.12861