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Elevated hepatocyte growth factor expression as an autocrine c‐Met activation mechanism in acquired resistance to sorafenib in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the third leading cause of cancer‐related deaths worldwide. Limitations in HCC treatment result due to poor prognosis and resistance against traditional radiotherapy and chemotherapies. The multikinase inhibitor soraf...

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Detalles Bibliográficos
Autores principales: Firtina Karagonlar, Zeynep, Koc, Dogukan, Iscan, Evin, Erdal, Esra, Atabey, Neşe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832867/
https://www.ncbi.nlm.nih.gov/pubmed/26790028
http://dx.doi.org/10.1111/cas.12891