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Inflammation in gastric cancer: Interplay of the COX‐2/prostaglandin E(2) and Toll‐like receptor/MyD88 pathways
Cyclooxygenase‐2 (COX‐2) and its downstream product prostaglandin E(2) (PGE(2)) play a key role in generation of the inflammatory microenvironment in tumor tissues. Gastric cancer is closely associated with Helicobacter pylori infection, which stimulates innate immune responses through Toll‐like rec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832872/ https://www.ncbi.nlm.nih.gov/pubmed/27079437 http://dx.doi.org/10.1111/cas.12901 |