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Characterization of pioglitazone cyclodextrin complexes: Molecular modeling to in vivo evaluation

AIMS: The objective of present study was to study the influence of different β-cyclodextrin derivatives and different methods of complexation on aqueous solubility and consequent translation in in vivo performance of Pioglitazone (PE). MATERIAL AND METHODS: Three cyclodextrins: β-cyclodextrin (BCD),...

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Detalles Bibliográficos
Autores principales: Bramhane, Dinesh M., Kulkarni, Preethi A., Martis, Elvis A. F., Pissurlenkar, Raghuvir R. S., Coutinho, Evans C., Nagarsenker, Mangal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832908/
https://www.ncbi.nlm.nih.gov/pubmed/27134470
http://dx.doi.org/10.4103/0975-7406.171680