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Combined sequence and sequence-structure based methods for analyzing FGF23, CYP24A1 and VDR genes

FGF23, CYP24A1 and VDR altogether play a significant role in genetic susceptibility to chronic kidney disease (CKD). Identification of possible causative mutations may serve as therapeutic targets and diagnostic markers for CKD. Thus, we adopted both sequence and sequence-structure based SNP analysi...

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Detalles Bibliográficos
Autores principales: Nagamani, Selvaraman, Singh, Kh. Dhanachandra, Muthusamy, Karthikeyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833053/
https://www.ncbi.nlm.nih.gov/pubmed/27114920
http://dx.doi.org/10.1016/j.mgene.2016.03.005