A paradoxical relationship between Resveratrol and copper (II) with respect to degradation of DNA and RNA

Resveratrol (R), a plant polyphenol, is known to reduce Cu (II) to Cu (I) generating reactive oxygen species that can cleave plasmid DNA. Here we report a surprising observation of a paradoxical relationship between R and Cu whereby plasmid DNA cleaving / degrading activity of R-Cu increased progres...

Descripción completa

Detalles Bibliográficos
Autores principales: Subramaniam, Siddharth, Vohra, Iqbal, Iyer, Aishwarya, Nair, Naveen K, Mittra, Indraneel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Observation Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833056/
https://www.ncbi.nlm.nih.gov/pubmed/27134724
http://dx.doi.org/10.12688/f1000research.7202.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833056/
https://www.ncbi.nlm.nih.gov/pubmed/27134724
http://dx.doi.org/10.12688/f1000research.7202.2

Ejemplares similares