Vitamin C modulates the metabolic and cytokine profiles, alleviates hepatic endoplasmic reticulum stress, and increases the life span of Gulo(−/−) mice

Suboptimal intake of dietary vitamin C (ascorbate) increases the risk of several chronic diseases but the exact metabolic pathways affected are still unknown. In this study, we examined the metabolic profile of mice lacking the enzyme gulonolactone oxidase (Gulo) required for the biosynthesis of asc...

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Detalles Bibliográficos
Autores principales: Aumailley, Lucie, Warren, Alessandra, Garand, Chantal, Dubois, Marie Julie, Paquet, Eric R., Le Couteur, David G., Marette, André, Cogger, Victoria C., Lebel, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833140/
https://www.ncbi.nlm.nih.gov/pubmed/26922388
http://dx.doi.org/10.18632/aging.100902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833140/
https://www.ncbi.nlm.nih.gov/pubmed/26922388
http://dx.doi.org/10.18632/aging.100902

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