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The Current State of Naïve Human Pluripotency

Naïve or ground state pluripotency is a cellular state in vitro which resembles cells of the preimplantation epiblast in vivo. This state was first observed in mouse embryonic stem cells and is characterized by high rates of proliferation, the ability to differentiate widely, and global hypomethylat...

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Detalles Bibliográficos
Autores principales: Dodsworth, Benjamin T., Flynn, Rowan, Cowley, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833179/
https://www.ncbi.nlm.nih.gov/pubmed/26119873
http://dx.doi.org/10.1002/stem.2085