Cargando…

The Current State of Naïve Human Pluripotency

Naïve or ground state pluripotency is a cellular state in vitro which resembles cells of the preimplantation epiblast in vivo. This state was first observed in mouse embryonic stem cells and is characterized by high rates of proliferation, the ability to differentiate widely, and global hypomethylat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dodsworth, Benjamin T., Flynn, Rowan, Cowley, Sally A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833179/ https://www.ncbi.nlm.nih.gov/pubmed/26119873 http://dx.doi.org/10.1002/stem.2085

Ejemplares similares

Activation‐Induced Cytidine Deaminase Regulates Fibroblast Growth Factor/Extracellular Signal‐Regulated Kinases Signaling to Achieve the Naïve Pluripotent State During Reprogramming
por: Kumar, Ritu, et al.
Publicado: (2019)

Derivation and Functional Analysis of Patient-Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease
por: Jiang, Yan, et al.
Publicado: (2012)

Artificial Intelligence Supports Automated Characterization of Differentiated Human Pluripotent Stem Cells
por: Marzec-Schmidt, Katarzyna, et al.
Publicado: (2023)

A Novel Role for miR‐1305 in Regulation of Pluripotency‐Differentiation Balance, Cell Cycle, and Apoptosis in Human Pluripotent Stem Cells
por: Jin, Shibo, et al.
Publicado: (2016)

Hes1 Desynchronizes Differentiation of Pluripotent Cells by Modulating STAT3 Activity
por: Zhou, Xinzhi, et al.
Publicado: (2013)

C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell‐Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
por: Dafinca, Ruxandra, et al.
Publicado: (2016)

Brief Report: Cell Cycle Dynamics of Human Pluripotent Stem Cells Primed for Differentiation
por: Shcherbina, Anna, et al.
Publicado: (2019)

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells
por: O'Brien, Carmel M., et al.
Publicado: (2017)

Concise Review: Modeling Neurodegenerative Diseases with Human Pluripotent Stem Cell‐Derived Microglia
por: Haenseler, Walther, et al.
Publicado: (2019)

Jun‐Mediated Changes in Cell Adhesion Contribute to Mouse Embryonic Stem Cell Exit from Ground State Pluripotency
por: Veluscek, Giulia, et al.
Publicado: (2016)

JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells
por: Neganova, Irina, et al.
Publicado: (2016)

Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells
por: Leung, Amy, et al.
Publicado: (2018)

Single‐Cell XIST Expression in Human Preimplantation Embryos and Newly Reprogrammed Female Induced Pluripotent Stem Cells
por: Briggs, Sharon F., et al.
Publicado: (2015)

Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells
por: Yang, Cheng‐Tao, et al.
Publicado: (2017)

Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Allergic Airway Inflammation in Mice
por: Sun, Yue-Qi, et al.
Publicado: (2012)

Concise Review: Measuring Physiological Responses of Human Pluripotent Stem Cell Derived Cardiomyocytes to Drugs and Disease
por: van Meer, Berend J., et al.
Publicado: (2016)

Accelerated differentiation of human pluripotent stem cells into neural lineages via an early intermediate ectoderm population
por: Walsh, Patrick, et al.
Publicado: (2020)

Human‐Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient‐Dependent Efficiency
por: Hallam, Dean, et al.
Publicado: (2018)

Brief Report: Inhibition of miR‐145 Enhances Reprogramming of Human Dermal Fibroblasts to Induced Pluripotent Stem Cells
por: Barta, Tomas, et al.
Publicado: (2015)

Multipotent Caudal Neural Progenitors Derived from Human Pluripotent Stem Cells That Give Rise to Lineages of the Central and Peripheral Nervous System
por: Denham, Mark, et al.
Publicado: (2015)

Deconstructing Retinal Organoids: Single Cell RNA‐Seq Reveals the Cellular Components of Human Pluripotent Stem Cell‐Derived Retina
por: Collin, Joseph, et al.
Publicado: (2019)

Deciphering the Transcriptional Landscape of Human Pluripotent Stem Cell-Derived GnRH Neurons: The Role of Wnt Signaling in Patterning the Neural Fate
por: Wang, Yafei, et al.
Publicado: (2022)

Global Proteomic and Methylome Analysis in Human Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affecting Proper Innate Immune Response Signaling
por: Requena, Jordi, et al.
Publicado: (2019)

Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity
por: Moris, Naomi, et al.
Publicado: (2018)

Zfp281 Functions as a Transcriptional Repressor for Pluripotency of Mouse Embryonic Stem Cells
por: Fidalgo, Miguel, et al.
Publicado: (2011)

Fibroblast-Derived Induced Pluripotent Stem Cells Show No Common Retroviral Vector Insertions
por: Varas, Florencio, et al.
Publicado: (2009)

Concise Review: Advances in Generating Hepatocytes from Pluripotent Stem Cells for Translational Medicine
por: Szkolnicka, Dagmara, et al.
Publicado: (2016)

Sars-Cov-2 Infects an Upper Airway Model Derived from Induced Pluripotent Stem Cells
por: Djidrovski, Ivo, et al.
Publicado: (2021)

Canonical Wnt/β-Catenin Regulation of Liver Receptor Homolog-1 Mediates Pluripotency Gene Expression
por: Wagner, Ryan T, et al.
Publicado: (2010)

CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones
por: Collin, Joseph, et al.
Publicado: (2019)

Endothelial Differentiation G Protein‐Coupled Receptor 5 Plays an Important Role in Induction and Maintenance of Pluripotency
por: Neganova, Irina, et al.
Publicado: (2019)

A Regulatory Network Involving β‐Catenin, e‐Cadherin, PI3k/Akt, and Slug Balances Self‐Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling
por: Huang, Tyng‐Shyan, et al.
Publicado: (2015)

Pluripotent Stem Cell‐Derived Hematopoietic Progenitors Are Unable to Downregulate Key Epithelial‐Mesenchymal Transition‐Associated miRNAs
por: Meader, Ellie, et al.
Publicado: (2017)

Using Zinc Finger Nuclease Technology to Generate CRX‐Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation
por: Collin, Joseph, et al.
Publicado: (2015)

CHD1L Regulated PARP1‐Driven Pluripotency and Chromatin Remodeling During the Early‐Stage Cell Reprogramming
por: Jiang, Bo‐Hua, et al.
Publicado: (2015)

Developing a simple method to enhance the generation of cone and rod photoreceptors in pluripotent stem cell‐derived retinal organoids
por: Zerti, Darin, et al.
Publicado: (2019)

Directed induction of alveolar type I cells derived from pluripotent stem cells via Wnt signaling inhibition
por: Kanagaki, Shuhei, et al.
Publicado: (2020)

P21-Activated Kinase 4 Pak4 Maintains Embryonic Stem Cell Pluripotency via Akt Activation
por: Cheng, Fangyuan, et al.
Publicado: (2022)

Elevated O‐GlcNAc Levels Activate Epigenetically Repressed Genes and Delay Mouse ESC Differentiation Without Affecting Naïve to Primed Cell Transition
por: Speakman, Christopher M., et al.
Publicado: (2014)

Concise Review: Generation of Neurons From Somatic Cells of Healthy Individuals and Neurological Patients Through Induced Pluripotency or Direct Conversion
por: Velasco, Iván, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_utumpqdegsrb71i6112p5dmqab