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Mitochondrial and inflammatory changes in sporadic inclusion body myositis

AIMS: Sporadic inclusion body myositis (sIBM) is the most common late onset muscle disease causing progressive weakness. In light of the lack of effective treatment, we investigated potential causes underlying muscle wasting. We hypothesized that accumulation of mitochondrial respiratory deficiency...

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Detalles Bibliográficos
Autores principales: Rygiel, Karolina A., Miller, James, Grady, John P., Rocha, Mariana C., Taylor, Robert W., Turnbull, Doug M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833191/
https://www.ncbi.nlm.nih.gov/pubmed/24750247
http://dx.doi.org/10.1111/nan.12149