Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition

In spite of the worldwide impact of diabetes on human health, the mechanisms behind glucose toxicity remain elusive. Here we show that C. elegans mutants lacking paqr-2, the worm homolog of the adiponectin receptors AdipoR1/2, or its newly identified functional partner iglr-2, are glucose intolerant...

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Detalles Bibliográficos
Autores principales: Svensk, Emma, Devkota, Ranjan, Ståhlman, Marcus, Ranji, Parmida, Rauthan, Manish, Magnusson, Fredrik, Hammarsten, Sofia, Johansson, Maja, Borén, Jan, Pilon, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833288/
https://www.ncbi.nlm.nih.gov/pubmed/27082444
http://dx.doi.org/10.1371/journal.pgen.1005982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833288/
https://www.ncbi.nlm.nih.gov/pubmed/27082444
http://dx.doi.org/10.1371/journal.pgen.1005982

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