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P2X7 Receptor Inhibition Improves CD34 T-Cell Differentiation in HIV-Infected Immunological Nonresponders on c-ART

Peripheral CD4+ T-cell levels are not fully restored in a significant proportion of HIV+ individuals displaying long-term viral suppression on c-ART. These immunological nonresponders (INRs) have a higher risk of developing AIDS and non-AIDS events and a lower life expectancy than the general popula...

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Detalles Bibliográficos
Autores principales: Menkova-Garnier, Inna, Hocini, Hakim, Foucat, Emile, Tisserand, Pascaline, Bourdery, Laure, Delaugerre, Constance, Benne, Clarisse, Lévy, Yves, Lelièvre, Jean-Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833302/
https://www.ncbi.nlm.nih.gov/pubmed/27082982
http://dx.doi.org/10.1371/journal.ppat.1005571