Nonlinear Dynamics in Gene Regulation Promote Robustness and Evolvability of Gene Expression Levels

Cellular phenotypes underpinned by regulatory networks need to respond to evolutionary pressures to allow adaptation, but at the same time be robust to perturbations. This creates a conflict in which mutations affecting regulatory networks must both generate variance but also be tolerated at the phe...

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Detalles Bibliográficos
Autores principales: Steinacher, Arno, Bates, Declan G., Akman, Ozgur E., Soyer, Orkun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833316/
https://www.ncbi.nlm.nih.gov/pubmed/27082741
http://dx.doi.org/10.1371/journal.pone.0153295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833316/
https://www.ncbi.nlm.nih.gov/pubmed/27082741
http://dx.doi.org/10.1371/journal.pone.0153295

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