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High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence

Cholera is the prime example of blood-group-dependent diseases, with individuals of blood group O experiencing the most severe symptoms. The cholera toxin is the main suspect to cause this relationship. We report the high-resolution crystal structures (1.1–1.6 Å) of the native cholera toxin B-pentam...

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Detalles Bibliográficos
Autores principales: Heggelund, Julie Elisabeth, Burschowsky, Daniel, Bjørnestad, Victoria Ariel, Hodnik, Vesna, Anderluh, Gregor, Krengel, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833353/
https://www.ncbi.nlm.nih.gov/pubmed/27082955
http://dx.doi.org/10.1371/journal.ppat.1005567