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Spatially coordinated replication and minimization of expression noise constrain three-dimensional organization of yeast genome
Despite recent advances, the underlying functional constraints that shape the three-dimensional organization of eukaryotic genome are not entirely clear. Through comprehensive multivariate analyses of genome-wide datasets, we show that cis and trans interactions in yeast genome have significantly di...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833423/ https://www.ncbi.nlm.nih.gov/pubmed/26932984 http://dx.doi.org/10.1093/dnares/dsw005 |