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Spatially coordinated replication and minimization of expression noise constrain three-dimensional organization of yeast genome

Despite recent advances, the underlying functional constraints that shape the three-dimensional organization of eukaryotic genome are not entirely clear. Through comprehensive multivariate analyses of genome-wide datasets, we show that cis and trans interactions in yeast genome have significantly di...

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Detalles Bibliográficos
Autores principales: Singh, Arashdeep, Bagadia, Meenakshi, Sandhu, Kuljeet Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833423/
https://www.ncbi.nlm.nih.gov/pubmed/26932984
http://dx.doi.org/10.1093/dnares/dsw005