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Touch and go: nuclear proteolysis in the regulation of metabolic genes and cancer
The recruitment of transcription factors to promoters and enhancers is a critical step in gene regulation. Many of these proteins are quickly removed from DNA after they completed their function. Metabolic genes in particular are dynamically regulated and continuously adjusted to cellular requiremen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833644/ https://www.ncbi.nlm.nih.gov/pubmed/26832397 http://dx.doi.org/10.1002/1873-3468.12087 |