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Revealing Assembly of a Pore-Forming Complex Using Single-Cell Kinetic Analysis and Modeling

Many biological processes depend on the sequential assembly of protein complexes. However, studying the kinetics of such processes by direct methods is often not feasible. As an important class of such protein complexes, pore-forming toxins start their journey as soluble monomeric proteins, and olig...

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Detalles Bibliográficos
Autores principales: Bischofberger, Mirko, Iacovache, Ioan, Boss, Daniel, Naef, Felix, van der Goot, F. Gisou, Molina, Nacho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833779/
https://www.ncbi.nlm.nih.gov/pubmed/27074682
http://dx.doi.org/10.1016/j.bpj.2016.02.035