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Revealing Assembly of a Pore-Forming Complex Using Single-Cell Kinetic Analysis and Modeling
Many biological processes depend on the sequential assembly of protein complexes. However, studying the kinetics of such processes by direct methods is often not feasible. As an important class of such protein complexes, pore-forming toxins start their journey as soluble monomeric proteins, and olig...
Autores principales: | Bischofberger, Mirko, Iacovache, Ioan, Boss, Daniel, Naef, Felix, van der Goot, F. Gisou, Molina, Nacho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833779/ https://www.ncbi.nlm.nih.gov/pubmed/27074682 http://dx.doi.org/10.1016/j.bpj.2016.02.035 |
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