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Immunogenicity of parenterally delivered plant-derived small and medium surface antigens of hepatitis B virus

KEY MESSAGE: Intramuscularly delivered plant-derived M-HBsAg was compared to S-HBsAg, and as a result elicited specific anti-preS2 antibodies and significantly higher titre of anti-HBs antibodies, together with IgG isotype profile indicating some Th1 polarisation, apart from the main Th2 response. A...

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Detalles Bibliográficos
Autores principales: Fedorowicz-Strońska, Olga, Kapusta, Józef, Czyż, Marcin, Kaczmarek, Małgorzata, Pniewski, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833783/
https://www.ncbi.nlm.nih.gov/pubmed/26905723
http://dx.doi.org/10.1007/s00299-016-1944-8