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Immunogenicity of parenterally delivered plant-derived small and medium surface antigens of hepatitis B virus
KEY MESSAGE: Intramuscularly delivered plant-derived M-HBsAg was compared to S-HBsAg, and as a result elicited specific anti-preS2 antibodies and significantly higher titre of anti-HBs antibodies, together with IgG isotype profile indicating some Th1 polarisation, apart from the main Th2 response. A...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833783/ https://www.ncbi.nlm.nih.gov/pubmed/26905723 http://dx.doi.org/10.1007/s00299-016-1944-8 |