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Activation of Wnt/ß-catenin signaling in ESC promotes rostral forebrain differentiation in vitro

Wnt/ß-catenin signaling is crucial for maintenance of pluripotent state of embryonic stem cell (ESC). However, it is unclear how Wnt/ß-catenin signaling affects the differentiation ability of ESC, especially with regard to rostral forebrain cells. Here, using Rax, rostral forebrain marker, and Wnt/ß...

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Detalles Bibliográficos
Autores principales: Takata, Nozomu, Sakakura, Eriko, Sasai, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833820/
https://www.ncbi.nlm.nih.gov/pubmed/26563247
http://dx.doi.org/10.1007/s11626-015-9975-y