Tor forms a dimer through an N-terminal helical solenoid with a complex topology

The target of rapamycin (Tor) is a Ser/Thr protein kinase that regulates a range of anabolic and catabolic processes. Tor is present in two complexes, TORC1 and TORC2, in which the Tor–Lst8 heterodimer forms a common sub-complex. We have determined the cryo-electron microscopy (EM) structure of Tor...

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Detalles Bibliográficos
Autores principales: Baretić, Domagoj, Berndt, Alex, Ohashi, Yohei, Johnson, Christopher M., Williams, Roger L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833857/
https://www.ncbi.nlm.nih.gov/pubmed/27072897
http://dx.doi.org/10.1038/ncomms11016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833857/
https://www.ncbi.nlm.nih.gov/pubmed/27072897
http://dx.doi.org/10.1038/ncomms11016

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