Cargando…

The dynamic organization of fungal acetyl-CoA carboxylase

Acetyl-CoA carboxylases (ACCs) catalyse the committed step in fatty-acid biosynthesis: the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. They are important regulatory hubs for metabolic control and relevant drug targets for the treatment of the metabolic syndrome and cancer. Eukaryotic A...

Descripción completa

Detalles Bibliográficos
Autores principales: Hunkeler, Moritz, Stuttfeld, Edward, Hagmann, Anna, Imseng, Stefan, Maier, Timm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833862/
https://www.ncbi.nlm.nih.gov/pubmed/27073141
http://dx.doi.org/10.1038/ncomms11196