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Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells

Evolutionally conserved Nanos RNA-binding proteins play crucial roles in germ cell development. While a mammalian Nanos family protein, NANOS2, is required for sexual differentiation of male (XY) germ cells in mice, the underlying mechanisms and the identities of its target RNAs in vivo remain elusi...

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Detalles Bibliográficos
Autores principales: Kato, Yuzuru, Katsuki, Takeo, Kokubo, Hiroki, Masuda, Aki, Saga, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833867/
https://www.ncbi.nlm.nih.gov/pubmed/27072294
http://dx.doi.org/10.1038/ncomms11272