RING finger protein 31 promotes p53 degradation in breast cancer cells

The atypical E3 ubiquitin ligase RNF31 is highly expressed in human breast cancer, the most frequent neoplastic lethality among women. Here, RNF31 depletion in breast cancer cells in combination with global gene expression profiling revealed p53 (TP53) signaling as a potential RNF31 target. Interest...

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Detalles Bibliográficos
Autores principales: Zhu, J, Zhao, C, Zhuang, T, Jonsson, P, Sinha, I, Williams, C, Strömblad, S, Dahlman-Wright, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833873/
https://www.ncbi.nlm.nih.gov/pubmed/26148235
http://dx.doi.org/10.1038/onc.2015.260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833873/
https://www.ncbi.nlm.nih.gov/pubmed/26148235
http://dx.doi.org/10.1038/onc.2015.260

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