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Whole Brain Radiotherapy and RRx-001: Two Partial Responses in Radioresistant Melanoma Brain Metastases from a Phase I/II Clinical Trial()(): A TITE-CRM Phase I/II Clinical Trial

BACKGROUND: Kim et al. report two patients with melanoma metastases to the brain that responded to treatment with RRx-001 and whole brain radiotherapy (WBRT) without neurologic or systemic toxicity in the context of a phase I/II clinical trial. RRx-001 is an reactive oxygen and reactive nitrogen spe...

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Detalles Bibliográficos
Autores principales: Kim, Michelle M., Parmar, Hemant, Cao, Yue, Pramanik, Priyanka, Schipper, Matthew, Hayman, James, Junck, Larry, Mammoser, Aaron, Heth, Jason, Carter, Corey A., Oronsky, Arnold, Knox, Susan J., Caroen, Scott, Oronsky, Bryan, Scicinski, Jan, Lawrence, Theodore S., Lao, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833892/
https://www.ncbi.nlm.nih.gov/pubmed/27084426
http://dx.doi.org/10.1016/j.tranon.2015.12.003