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Analysis of PI3K/mTOR Pathway Biomarkers and Their Prognostic Value in Women with Hormone Receptor–Positive, HER2-Negative Early Breast Cancer()

BACKGROUND: The PI3K/AKT/mTOR pathway alterations have been shown to play significant roles in the development, progression, and metastatic spread of breast cancer. Furthermore, they have been implicated in the process of drug resistance, especially endocrinal therapies. In this study, we aimed to d...

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Detalles Bibliográficos
Autores principales: Azim, Hamdy A., Kassem, Loay, Treilleux, Isabelle, Wang, Qing, El Enein, Mona Abu, Anis, Shady E., Bachelot, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833894/
https://www.ncbi.nlm.nih.gov/pubmed/27084427
http://dx.doi.org/10.1016/j.tranon.2016.01.001