BAGEL: a computational framework for identifying essential genes from pooled library screens

BACKGROUND: The adaptation of the CRISPR-Cas9 system to pooled library gene knockout screens in mammalian cells represents a major technological leap over RNA interference, the prior state of the art. New methods for analyzing the data and evaluating results are needed. RESULTS: We offer BAGEL (Baye...

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Detalles Bibliográficos
Autores principales: Hart, Traver, Moffat, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833918/
https://www.ncbi.nlm.nih.gov/pubmed/27083490
http://dx.doi.org/10.1186/s12859-016-1015-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833918/
https://www.ncbi.nlm.nih.gov/pubmed/27083490
http://dx.doi.org/10.1186/s12859-016-1015-8

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