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BAGEL: a computational framework for identifying essential genes from pooled library screens
BACKGROUND: The adaptation of the CRISPR-Cas9 system to pooled library gene knockout screens in mammalian cells represents a major technological leap over RNA interference, the prior state of the art. New methods for analyzing the data and evaluating results are needed. RESULTS: We offer BAGEL (Baye...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833918/ https://www.ncbi.nlm.nih.gov/pubmed/27083490 http://dx.doi.org/10.1186/s12859-016-1015-8 |