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Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay

BACKGROUND: Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging potential of nanomaterials are scarce. Traditionally, eye irritation testing was performed using rabbits. The OECD Test Guideline 437...

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Detalles Bibliográficos
Autores principales: Kolle, Susanne N., Sauer, Ursula G., Rey Moreno, Maria C., Teubner, Wera, Wohlleben, Wendel, Landsiedel, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833924/
https://www.ncbi.nlm.nih.gov/pubmed/27083156
http://dx.doi.org/10.1186/s12989-016-0128-6