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Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay
BACKGROUND: Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging potential of nanomaterials are scarce. Traditionally, eye irritation testing was performed using rabbits. The OECD Test Guideline 437...
Autores principales: | Kolle, Susanne N., Sauer, Ursula G., Rey Moreno, Maria C., Teubner, Wera, Wohlleben, Wendel, Landsiedel, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833924/ https://www.ncbi.nlm.nih.gov/pubmed/27083156 http://dx.doi.org/10.1186/s12989-016-0128-6 |
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