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Propofol Ameliorates Calpain-induced Collapsin Response Mediator Protein-2 Proteolysis in Traumatic Brain Injury in Rats

BACKGROUND: Collapsin response mediator protein-2 (CRMP2), a multifunctional cytosolic protein highly expressed in the brain, is degraded by calpain following traumatic brain injury (TBI), possibly inhibiting posttraumatic neurite regeneration. Lipid peroxidation (LP) is involved in triggering posti...

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Detalles Bibliográficos
Autores principales: Yu, Yun, Jian, Min-Yu, Wang, Yun-Zhen, Han, Ru-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834009/
https://www.ncbi.nlm.nih.gov/pubmed/25836613
http://dx.doi.org/10.4103/0366-6999.154298