Cargando…
Propofol Ameliorates Calpain-induced Collapsin Response Mediator Protein-2 Proteolysis in Traumatic Brain Injury in Rats
BACKGROUND: Collapsin response mediator protein-2 (CRMP2), a multifunctional cytosolic protein highly expressed in the brain, is degraded by calpain following traumatic brain injury (TBI), possibly inhibiting posttraumatic neurite regeneration. Lipid peroxidation (LP) is involved in triggering posti...
Autores principales: | Yu, Yun, Jian, Min-Yu, Wang, Yun-Zhen, Han, Ru-Quan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834009/ https://www.ncbi.nlm.nih.gov/pubmed/25836613 http://dx.doi.org/10.4103/0366-6999.154298 |
Ejemplares similares
-
Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration
por: Zhang, Jian-Nan, et al.
Publicado: (2016) -
Calpain-2 Inhibitors as Therapy for Traumatic Brain Injury
por: Baudry, Michel, et al.
Publicado: (2023) -
Calpain-mediated proteolysis as driver and modulator of polyglutamine toxicity
por: Incebacak Eltemur, Rana Dilara, et al.
Publicado: (2022) -
Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity
por: Khan, Mushfiquddin, et al.
Publicado: (2018) -
Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury
por: Wilson, Sarah M., et al.
Publicado: (2014)