Effect of hepatic or renal impairment on the pharmacokinetics of evacetrapib

PURPOSE: The aim of this study is to investigate the effect of hepatic or renal impairment on the pharmacokinetics of a single 130-mg evacetrapib dose. METHODS: Two open-label, parallel-design studies in males and females with normal hepatic function or Child-Pugh mild, moderate, or severe hepatic i...

Descripción completa

Detalles Bibliográficos
Autores principales: Small, David S., Zhang, Wei, Royalty, Jane, Cannady, Ellen A., Downs, Delyn, Ortega, Demetrio, Suico, Jeffrey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Pharmacokinetics and Disposition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834099/
https://www.ncbi.nlm.nih.gov/pubmed/26857125
http://dx.doi.org/10.1007/s00228-016-2017-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834099/
https://www.ncbi.nlm.nih.gov/pubmed/26857125
http://dx.doi.org/10.1007/s00228-016-2017-1

Ejemplares similares