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Effect of hepatic or renal impairment on the pharmacokinetics of evacetrapib

PURPOSE: The aim of this study is to investigate the effect of hepatic or renal impairment on the pharmacokinetics of a single 130-mg evacetrapib dose. METHODS: Two open-label, parallel-design studies in males and females with normal hepatic function or Child-Pugh mild, moderate, or severe hepatic i...

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Detalles Bibliográficos
Autores principales:	Small, David S., Zhang, Wei, Royalty, Jane, Cannady, Ellen A., Downs, Delyn, Ortega, Demetrio, Suico, Jeffrey G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2016
Materias:	Pharmacokinetics and Disposition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834099/ https://www.ncbi.nlm.nih.gov/pubmed/26857125 http://dx.doi.org/10.1007/s00228-016-2017-1

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