Systems Pharmacology Approach for Prediction of Pulmonary and Systemic Pharmacokinetics and Receptor Occupancy of Inhaled Drugs

Pulmonary drug disposition after inhalation is complex involving mechanisms, such as regional drug deposition, dissolution, and mucociliary clearance. This study aimed to develop a systems pharmacology approach to mechanistically describe lung disposition in rats and thereby provide an integrated un...

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Detalles Bibliográficos
Autores principales: Boger, E, Evans, N, Chappell, M, Lundqvist, A, Ewing, P, Wigenborg, A, Fridén, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834131/
https://www.ncbi.nlm.nih.gov/pubmed/27104089
http://dx.doi.org/10.1002/psp4.12074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834131/
https://www.ncbi.nlm.nih.gov/pubmed/27104089
http://dx.doi.org/10.1002/psp4.12074

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